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Is ketoconazole useful to prevent hair loss?

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Is ketoconazole useful to prevent hair loss?

Females usually detect hair loss faster than men, but baldness or alopecia is more common in males due to their hormonal profile. Testosterone has a significant role in male pattern baldness because this hormone is transformed into DHT in the hair follicle, and DHT causes destruction of this structure in the scalp. If you no longer have hair follicles because they are destroyed, you end up with alopecia, and your hair won’t grow back again.

That’s why alopecia is more common in males with bald parents, uncles, or grandparents. It has a genetic predisposition to it, but there’s something we can do to solve the problem. As you will see in this article, ketoconazole, an antifungal agent, is also useful for some cases of alopecia, especially androgenetic alopecia.

Androgenetic alopecia and ketoconazole

Androgenetic alopecia is the most common cause of hair loss in males. It causes a male pattern baldness, which affects the midfrontal and frontoparietal scalp. As it advances, it goes up to the superior portion of the scalp, and it is more common in older Caucasians. It is estimated that around 50% of Caucasian males will develop a form of androgenic alopecia when they reach 50 years old. However, even though genetics are essential, several environmental factors play an important role, including stress, smoking, and consumption of alcohol.

What happens is that circulating testosterone is converted into an active form called DHT or dihydrotestosterone. This hormone binds to their receptors in the scalp, and trigger a dysfunction and later destruction of the hair follicles.

So far, the only treatment approved by the FDA includes oral finasteride and topical minoxidil. This combination is useful to prevent the conversion into DHT and stimulate hair growth, respectively. However, it is not very useful for some patients, and others may develop adverse effects. That is why other therapies have been implemented, including laser light therapy, dutasteride, platelet-rich plasma, hair transplants, and topical ketoconazole.

Ketoconazole is an antifungal agent included in the group of imidazole substances. It inhibits the synthesis of ergosterol, a material that is found in the cell membrane of fungi. But besides its antifungal properties, it is also an anti-inflammatory that inhibits an enzyme called 5-lipooxygenase and blocks the synthesis of testosterone and the concentration of DHT. As such, ketoconazole is another potential treatment of androgenetic alopecia, and it has been studied in animals and humans with promising results.

Is ketoconazole useful to promote hair growth?

According to studies, ketoconazole can be useful in promoting hair growth in patients with androgenetic alopecia. For example, in one of them, the researchers used a ketoconazole lotion, which was meant to be used daily for one year. During the follow-ups, patients who used ketoconazole showed an improvement and significant hair regrowth. Still, according to this study, they needed to wait for a long time to start seeing results.

Other studies evaluated using a ketoconazole shampoo along with 1 mg oral finasteride. The control group included one with oral finasteride alone and another with oral finasteride and 2% minoxidil twice a day. In combination with finasteride, ketoconazole works even better, and the patients had a significant improvement in their condition. Combined treatment was more useful than finasteride alone, and no side effects were reported. However, there was no significant difference between ketoconazole and minoxidil as a side treatment. As such, it is considered a suitable alternative to minoxidil in these patients.

And one of the first studies of ketoconazole for hair loss showed that treating patients with ketoconazole shampoo can lead to potential hair regrowth after 6 months, which increases as the treatment continues and plateaus after one year and 3 months. In comparison, patients who used shampoo with no medication at all remained stable and sometimes experienced a significant increase in the severity of their condition.

Should you choose to use a shampoo with ketoconozale, we recommend Hair Restoration Laboratories’ Professional Strength Hair Restore Shampoo.  It contains 1% ketoconozale along with numerous other ingredients that have been clinically proven to help prevent hair loss and promote hair growth. 

The present and future of ketoconazole treatment for alopecia

Currently, androgenetic alopecia is a health problem with significant psycho social consequences, and there is a need of established and alternative therapies for these patients. The clinical studies and animal research about ketoconazole for the treatment of alopecia always support its use in some way. 

The application of this alternative can be useful in patients with androgenetic alopecia and concomitant seborrheic dermatitis, primarily because ketoconazole has been described as a useful therapy against Malassezia infections. It can also be a safe alternative for women with androgenetic alopecia who are unable to use finasteride treatment or display limited results with minoxidil.

Still, to study ketoconazole in the treatment of androgenic alopecia, we still need more large-scale prospective studies to figure out the exact mechanisms by which ketoconazole promotes hair regrowth. In any case, the absence of side effects of topical ketoconazole makes it a useful candidate to use as an adjunctive therapy to treat male and female patients with androgenetic alopecia, and well designed, and large-scale studies are still necessary to evaluate its efficacy on the long-term.

HEALTH

People getting smarter with their healthy food choice-2020

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People getting smarter with their healthy food choice-2020

Just like there are advancements in the other field, people now are getting with their healthy Food choice of eating and maintaining a healthy diet. This is followed by the selection of hygienic and environment-friendly health and sanitary products. People prefer to ignore the usage of plastic and use real wood and other things. They are getting wiser about the products they consume and this is also accompanied by efficient packaging. All of this has an impact on the environment of us.

Today we luckily had a chance of taking an interview with the director of one of such a website that promotes the usage and selling of eco-friendly products for daily use. Yes, we are talking about Jan Fridich. Let us go through the conversation we had with him in the below section:

So people have been hearing a lot about your website, tell us something more about it and yourself”-

“Ummm…. Yeah, you’re right. My website known as “Jxnfrd.shop” is in Austria. I am from Austria. I was born here in Sep 1997. As long as it is about the website, it is meant to be a digital platform where we aim to provide customer support to English people 24/7.  We incorporated it on October 3rd, 2019. Our true aim is to promote the use of eco-friendly products to save our mother earth from being destroyed by its residents. The choice is ours. It is only us who can take the initiative of using products other than plastic”.

“So what material do you prefer to be used instead”?

Upon this question, Jan was quite curious to tell us that: “we prefer using Bamboo and real wood for use. This will lead to less utilization of plastic and other material manufacturing which will eventually lead to a healthier environment and healthy people “.

Healthy people? How?

“Yeah, “healthy people”. This is because we deal online in all the top-selling products from 2019 and 2020. You can find healthier food products at our online store that are eco-friendly and promote eco-friendly food for healthier mother earth. Products of daily use for hygiene just like toothbrushes, are also eco-friendly so that you don’t get your gums hurt or bleed them inconsequently. You find well managed and quality products at our store, try it once and you will be falling in love with our service and customer support. ”

So how do people approach your website and avail its service?

You guys can find everything on the internet online. All you have to do is a chat request at our website interface and it will lead you to -70% on our products. Our support team aims to provide their customers with the best quality products followed by the cheapest rates for their customers’ from Austria. Also, shipping across Austria is free. For services, you will create an account and sign up for a newsletter. You get a 1$ / month membership at our store JXNFRD LTD. We will provide you customer support through live chat. You also see the products we sell from Instagram and Facebook ads.”

Where did you get the inspiration from?

“Well, the inspiration comes from my exceptional love for food. I have always been a food lover and it makes me realize the importance of eating healthier and maintaining a good diet. You can see my food blog on Instagram where I share a lot about the food I make and like. You can also follow the following link to explore more. Also, you can check my store out here. The product details are given here where you can check them out.”

Must check out my website and share it with your family and friends, you will surely love the services.

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HEALTH

Why Choose 3D Mesh Hernia Treatment Hospital in Gurgaon

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3D Mesh Hernia Treatment Hospital in Gurgaon

3D Mesh Hernia

Are you suffering from a hernia? Did you know that owing to the complex lifestyle can make you suffer from a hernia? Yes! Obesity, consuming junk food, stress, smoking, dietary choices with lack of fibers, are just some of the lifestyle choices that put people at the risk of having a hernia. So, if you are a corporate worker, working with an MNC in Gurgaon or any other major city, you are more likely to suffer from one.

A hernia is a bulge or protrusion of body tissue or organ through the structure that normally contains it. It results due to weak spots present in the abdominal muscle walls,  groin, upper thigh, chest, or hips. Hernias are found to affect both men and women equally, increasing the chances of advanced age.

What are the causes and symptoms of a hernia?

Hernias are classified into different types based on their origin and severity. Some common causes of hernia include:

  • Weak abdominal muscles or tissues
  • Bowel obstruction and constipation
  • The strain on lifting heavy objects
  • Complications during or after pregnancy
  • Severe coughing
  • Lack of nutrition

The symptoms to identify hernia are:

  • A bulge in the groin or abdominal area
  • Pain or burning sensation near the bulge
  • Darkening of the bulge
  • Chest pain
  • Acid reflux
  • Nausea and vomiting
  • Difficulty swallowing
  • Pain when coughing or lifting heavy objects

What is a 3D mesh Hernia?

Hernia mesh, also known as surgical mesh, is a medical device that is used to cover up the hernia to reduce the chances of recurrence. The 3D mesh repair technique involves the usage of a polypropylene mesh which ensures that the hernia is covered from above, centre, and below. 3D mesh repair supports the damaged tissue around the hernias as it heals.

During the procedure, surgeons place the mesh surrounding the hernia and attach them at the site with the help of stitches, staples or glue. This way, the pores in the mesh allow the tissue to grow into the device, securing the hernia and strengthening the hernia repair.  Hospitals in Gurgaon use hernia mesh for repairing in almost nine out of 10 surgeries.

Why choose a 3D Mesh Hernia treatment hospital in Gurgaon?

Gurgaon is considered to be a corporate hub, Its people are usually rich, or well-educated urban professionals who work for some of the biggest firms in the world. Corporate life makes the life of people more complex where they tend to choose unhealthy food and lifestyle habits increasing their likelihood to develop a hernia.

But, on one side where Gurgaon is considered to be a corporate hub, it also has numerous hospitals that can cater to all types of hernia by providing the most advanced treatment care for a hernia. One can choose from different types of treatment to a varied range of expenses to get the best hernia treatment. Not only the hospitals but the team of doctors in the Gurgaon hospitals are well experienced and can provide treatment best suited for you based on your exact needs.

Hospitals in Gurgaon are updated with the latest technology that offers advanced treatment options to the patients,   such as laser surgery, 3D mesh surgery, and reconstructive surgeries for a hernia.

3D mesh surgery for inguinal hernia repair

The 3D mesh surgery is preferred for the repair of an inguinal hernia. The procedure uses Polypropylene mesh to cover and repair the from above, below, and centre. It is an easy and quick method that repair hernia, providing relief and recovery faster.

3D mesh surgery for umbilical hernia repair

The 3D mesh surgery aims to repair the umbilicus, instead of removing it as other methods of treatment propose to do. This repair occurs from the anterior and posterior aspects. The procedure involves bringing the umbilicus to its original position and then repairing it, with a negligible recurrence rate. The 3D mesh surgery takes a short time and you can even go home on the same day.

Advantages of 3D Mesh Repair:

  • Minimal incision, a lesser number of stitches
  • Negligent chances of recurrence
  • Performed under local anesthesia
  • Faster discharge from hospital
  • Minimal recovery time
  • No risk of groin pain as stitches do not fix the mesh

Why opt for 3D mesh repair treatment in Gurgaon?

There are numerous hospitals or proctology clinics in Gurgaon which offer USFDA approved laser devices that are carefully handled and used by experts.

Gurgaon has various hernia removal surgery options, including the 3D mesh hernia removal technique. The advantages of this technique are more than other surgical procedures. Moreover, one should get treated from the hospitals in Gurgaon as they offer:

  • Cost-effective surgery
  • Post-operative care
  • Higher success rates
  • Painless surgery
  • Experienced doctors
  • Updated infrastructure
  • Proper instruments available
  • Detailed consultation with doctors
  • Pre and post-diet consultations

Summary

Talk to your doctor and know if, with your medical history, the 3D mesh repair surgery can be recommended. If yes, hospitals in Gurgaon can offer you the best treatment in this technique.

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HEALTH

The Best Bread for an Alkaline Diet

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The Best Bread for an Alkaline Diet

If you plan to try a vegan diet or already take such a menu, you should have heard about the alkaline diet. Simply, the diet is designed with high-alkalized stuff.

A very common misconception goes that you have to cut many substances from your menu if you follow alkaline foodstuffs. Though the alkaline menu is restricted, you can still enjoy your favorite foods in a tricky way.

Bread is a regular meal we take in the breakfast that has plenty of high pH ingredients. We are going to share the best bread for an alkaline diet you can prepare at home. For a more alkaline diet, you can check this out as well.

What is Alkaline Diet?

Honduran herbalist Alfredo Bowman, also called Dr. Sebi, introduced some high pH recipes. These diets are also called acid-alkaline meals.

In this diet, you are restricted to avoid a number of listed foods like wheat, coffee, beef, sugary foods, pasta etc.

Alkaline ash menus claimed to have natural protection against several maladies. Our bodies burn foods to generate calories to provide us with strength. After burning the consumed foods, our body keeps the acidic wastes inside.

The goal of alkaline food is to maintain a balanced acidic degree in the human body.

Making the Alkaline Electric Spelt Bread

This alkaline bread recipe is the best alternative to the regular bread. You can prepare this feast following these steps.

Ingredients:

Spelt flour, grape seed oil, agave, sparkling spring water, sea salt and sesame seeds.

For mixing and preparing, you need a dough hook mixer and a loaf pan.

Process:

  • Take four cups of spelt flour and 2 tablespoons of sea salt. Put them into the mixer machine and mix for about ten seconds.
  • Add ¼ cup of agave and continue the blending.
  • Make a light layer of grapeseed oil on the dough hook and continue the mixing. You need to add one cup of sparkling spring water at a time to mix the ingredient well.
  • If the flour spread around the edge of the bowl, abrade them to the mixer and blend again with a moderate speed for around five minutes.
  • If the dough seems sticky, add about a half cup of spelt flour again or as required.
  • Now cover a loaf pan lightly with oil and put the dough into it. Place the lid and wait for an hour.
  • Heat your oven before baking to 350 degrees Fahrenheit (176°C). Now, bake it for fifty minutes to one hour.
  • Now make it cool properly before eating.

Alkaline electric Spelt bread is a quite healthy and low acidic meal. You can replace your regular bread with this dish completely. Each ingredient used to prepare this acid-alkaline food is rich in the required minerals and antioxidants for our bodies.

If you have a chronic disease like diabetes or high blood pressure, this can be a suggested physical wellness recipe. However, if you want to regularly consider this diet, consult with an experienced physician for a better outcome.

 

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